I was playing with PaiMei and trying to get some initial stuff working on Pai Mei Reverse Engineering framework by Pedram Amini.
It was a smooth ride until the following steps:
1. Install MySQL
2. Install wxPython
3. Install GDE and uDraw

There was a slight problem in the __install_requirements.py file that it would always look at C:\Program Files for the files whereas my files were in S:\Program Files.
Either way a small change from C to S in the __install_requirements.py did the trick. Thereafter, when I ran __setup_mysql.py script I got the following error:

_mysql_exceptions.OperationalError: (1101, “BLOB/TEXT column ‘eax_deref’ can’t have a default value”)

Seems like MySQL should not be running in “strict” mode while you run this script. I got this information from the following link:
http://paimei.openrce.org:8000/ticket/5